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Updates on Clostridioides difficile in Europe

Name: Updates on Clostridioides difficile in Europe
Brand: Springer, Berlin
SKU: 9783031421075
Price: 63014 HUF
Availability: InStock

Advances in Microbiology, Infectious Diseases and Public Health Volume 18

Szerző: Paola Mastrantonio, Maja Rupnik

Nyelv:

Kötés: Kemény kötésű

Kiadó: Springer, Berlin

Elérhetőség: Beszállítói készleten

Küldés 10-13 napon belül

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This fully updated second edition outlines the currently available clinical, epidemiological and exp...

Információk a könyvről

Szerző

Paola Mastrantonio, Maja Rupnik

Nyelv

Angol

Kötés

Könyv - Kemény kötésű

Kiadva

2023

oldal

372

EAN

9783031421075

Enbook ID

43829994

Kiadó

Springer, Berlin

Súly

896

Méretek

178 x 254

Teljes leírás

This fully updated second edition outlines the currently available clinical, epidemiological and experimental data on Clostridioides difficile infections(CDI) with special emphasis on studies and results achieved in Europe. The incidence and severity of CDI has increased significantly over the last decade, and the book explains why C. difficile, recently reclassified as Clostridioides difficile, remains a significant challenge, also from economic perspective, to health care systems all over the world. The different reservoirs of this ubiquitous microorganism are reviewed as well as the different factors contributing to its virulence, such as toxins and biofilm formation. The rapid evolution of antibiotic resistance is clearly a concern and in a specific way can influence the CDI epidemiology. Additionally, new emerging strains and comparative genomics studies are taken into consideration for their relevance from epidemiological and evolutionary point of view. The book also gives an overview on diagnostics, therapy and surveillance, all of which are still challenging. Therefore, a closer look is taken on the effect of probiotics as an alternative to antibiotics, for prevention and treatment of CDI. Fecal transplantation from healthy donors, passive immunotherapies and vaccines for patients with recurrences are also discussed in dedicated chapters. New topics included sporulation and membrane vesicles in C. difficile. The book closes with a summary of the history and the achievements of the European Society of Clinical Microbiology and Infectious Diseases Study Group for Clostridium difficile (ESGCD) written by the current and past presidents of the Society. It is the aim of this book to raise awareness on CDI and to disseminate updated information on its prevention, diagnosis and treatment.