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Könyv Validation of Alternative Methods for Toxicity Testing CHANTRA ESKES

Validation of Alternative Methods for Toxicity Testing

Szerző: CHANTRA ESKES
Nyelv: Angol
Kötés: Puha kötésű
Kiadó: Springer International Publishing AG
Elérhetőség: Beszállítói készleten
Küldés 5-8 napon belül
65 093 Ft
This book provides information on best practices and new thinking regarding the validation of altern...

Információk a könyvről

Szerző
CHANTRA ESKES
Nyelv
Angol
Kötés
Könyv - Puha kötésű
Kiadva
2018
oldal
407
EAN
9783319816128
ISBN
9783319816128
Enbook ID
19784816
Kiadó
Springer International Publishing AG
Súly
6438
Méretek
155 x 235 x 24

Teljes leírás

This book provides information on best practices and new thinking regarding the validation of alternative methods for toxicity testing. It covers the validation of experimental and computational methods and integrated approaches to testing and assessment. Validation strategies are discussed for methods employing the latest technologies such as tissue-on-a-chip systems, stem cells and transcriptomics, and for methods derived from pathway-based concepts in toxicology. Validation of Alternative Methods for Toxicity Testing is divided into two sections, in the first, practical insights are given on the state-of-the-art and on approaches that have resulted in successfully validated and accepted alternative methods. The second section focuses on the evolution of validation principles and practice that are necessary to ensure fit-for-purpose validation that has the greatest impact on international regulatory acceptance of alternative methods. In this context validation needs to keep pace with the considerable scientific advancements being made in toxicology, the availability of sophisticated tools and techniques that can be applied in a variety of ways, and the increasing societal and regulatory demands for better safety assessment. This book will be a useful resource for scientists in the field of toxicology, both from industry and academia, developing new test methods, strategies or techniques, as well as Governmental and regulatory authorities interested in understanding the principles and practicalities of validation of alternative methods for toxicity testing.

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