Több mint 4 millió cím angol és más nyelveken! Fedezd fel új történetedet még ma!

Rendelés állapotának ellenőrzése

Kapcsolat

G Protein-Coupled Receptors - Molecular Pharmacology - From Academic Concept to Pharmaceutical Research

Szerző: Vauquelin

Nyelv:

Kötés: Kemény kötésű

Kiadó: John Wiley & Sons Inc

Elérhetőség: 50 % esély

Keressük az egész világon

76 491 Ft

G protein-coupled receptors (GPCRs) are membrane proteins that transduce a vast array of extracellul...

Információk a könyvről

Szerző

Vauquelin

Nyelv

Angol

Kötés

Könyv - Kemény kötésű

Kiadva

2007

oldal

264

EAN

9780470516478

ISBN

047051647X

Enbook ID

04083249

Kiadó

John Wiley & Sons Inc

Súly

698

Méretek

174 x 246 x 18

Teljes leírás

G protein-coupled receptors (GPCRs) are membrane proteins that transduce a vast array of extracellular signals into intracellular reactions ranging from cell-cell communication processes to physiological responses. They play an important role in a variety of diseases from cancer and diabetes, to neurodegenerative, inflammatory and respiratory disorders. GPCRs are therefore of utmost interest in drug development: over half of all prescription drugs currently on the market act by targeting these receptors directly or indirectly. G Protein-coupled Receptors: Molecular Pharmacology provides a clear summary of the current knowledge in this fast-evolving field. The book sets out with an introduction to signalling molecules and their receptors, and an overview of the technical approaches used to investigate these interactions. Structural, functional and especially pharmacological aspects of GPCRs are then discussed in more detail and much attention is devoted to the analysis and interpretation of experimental data. The now widespread use of recombinant cell lies, receptor mutants and related artifices in drug research is critically evaluated. Special attention is also devoted to topical but often poorly understood concepts, such as insurmountable antagonism, inverse agonism and allosteric interactions. By combining general information with the major state-of-the-art concepts in GPCR-research, this outstanding book equips the reader with the necessary background for understanding and critically evaluating the current literature. Written by two experts from academia and industry, G Protein-coupled Receptors: Molecular Pharmacology offers a unique view of academic and applied approaches aiming to reveal new ideas in pharmaceutical research. The book is of interest to anyone involved in drug development and preclinical research and those who need to function within multi-disciplinary teams in the pharmaceutical industry: from investigators to product managers or clinicians who seek to have a broad mechanistic understanding of drug-receptor interactions. It is also an invaluable resource for final year undergraduate and postgraduate students in pharmacology and cell and molecular biology.

Leggyakrabban keresett

Categories

Authors

Publishers

Termékek

Termékek

Leggyakrabban keresett

Categories

Authors

Publishers

Termékek

Termékek

G Protein-Coupled Receptors - Molecular Pharmacology - From Academic Concept to Pharmaceutical Research

Információk a könyvről

Teljes leírás

Érdekelheti

Fundamentals of Municipal Bonds

Privatization of Hope

Engineering Excellence: Measure and Achieve Benchmark Performance

High School Boysapo Fishing Trip

Robust Nonlinear Controller Design

Cage of Water

Honor of the Clan

Castle Rackrent

Flashman and the Dragon

Practical Handbook for the Boss

Countries Of The Mind; Essays In Literary Criticism

Advances in Biomembranes and Lipid Self-Assembly

Beyond Strategy

Azok a vásárlók, akik ezt a könyvet megvásárolták, a következőket is megvásárolták

La Razon de Estar Contigo

Diario Multigeneracional Guiado para Bisavos

Résister...

El temps i el clima de Menorca

Curso de la Gracia - Lider

Política de la Liberación I: Historia mundial y crítica

Ihtilal 1 - Zelzele Kutulu Ciltli Set

L'Alimentation intuitive